Molecular Surveillance for Multidrug-Resistant Plasmodium falciparum, Cambodia

نویسندگان

  • Naman K. Shah
  • Alisa P. Alker
  • Rithy Sem
  • Agustina Ika Susanti
  • Sinuon Muth
  • Jason D. Maguire
  • Socheat Duong
  • Frederic Ariey
  • Steven R. Meshnick
  • Chansuda Wongsrichanalai
چکیده

We conducted surveillance for multidrug-resistant Plasmodium falciparum in Cambodia during 2004-2006 by assessing molecular changes in pfmdr1. The high prevalence of isolates with multiple pfmdr1 copies found in western Cambodia near the Thai border, where artesunate-mefloquine therapy failures occur, contrasts with isolates from eastern Cambodia, where this combination therapy remains highly effective.

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عنوان ژورنال:
  • Emerging Infectious Diseases

دوره 14  شماره 

صفحات  -

تاریخ انتشار 2008